Sentence examples for models of template from inspiring English sources
Cell-free models of template directed PrPC misfolding (or conversion to PrPSc) have demonstrated that PrPSc can induce a conformational change in PrPC, rendering it protease resistant (referred to as PrPres) [4], [5], [6] and infectious under prescribed conditions [7].
FINDSITEX on the other hand, as mentioned, employs homology modeling methods to model structures of template proteins, which are then aligned and compared to target proteins using a global structure alignment method.
The template-driven self-assembly technique was effective when a combination of 5 nm silica (as a model of an inorganic nanoparticle) and two different sizes of monodispersed polystyrene (PS) spheres (as models of the template) were self-assembled to produce a composite silica/PS template.
Each of the entries in the virtual library was probed for its possible interactions with molecular models of the template molecules.
Homology modeling and superposition of models to templates was performed using the Geno3D tool available on-line at the IBCP-PBIL server http://geno3d-pbil.ibcp.fr[ 42].
The modeling of the template is shown in Figure 8A and of LdTah1 using this template is shown in Figure 8B.
It can detect and estimate pose of objects simultaneously from the pose of the model of matched template image.
The LLR distance contrasts the fit score of a test frame with its best model against its fit score with the best model of the template frame, and it therefore compares the two frames indirectly through the models.
Therefore, to capture an "average" DFG-out conformation, we developed an approach, DFGmodel, to generate DFG-out models for the target kinase based on homology modeling of multiple template structures.
An essential advantage of TASSER over traditional comparative modeling methods, which often deteriorate the quality of template models, is its ability to drive the template structures closer to the native than the input templates.
It also takes as input modeling knowledge about the studied domain, represented as a library of template model components, i.e., entities and processes.
