Sentence examples for models of sporadic from inspiring English sources

Mast cells have also been shown to affect the incidence and severity of neoplasia in models of sporadic colon cancers [22], [23].

In this study, we assessed the expression and role of Smad7 in human and mouse models of sporadic CRC.

Furthermore, functional studies in rodents have shown potent anticarcinogenic effects for 5-ASA in models of sporadic and colitis-associated cancer (4 6).

In conditional GEMMs, such as the KPC model, genetic alterations are often activated simultaneously in a large number of cells during development in the mouse, even though they are used as models of sporadic, non-inherited human cancers.

In cellular models of sporadic AD, application of Aβ has been shown to cause the formation of Ca2+-permeable pores in bilayer membranes (Arispe et al., 1993) or thinning of membranes resulting in increased ion permeability (Kayed et al., 2004).

This study was designed to investigate the protective effects of tan IIA against memory deficits induced by streptozotocin (STZ) in a model of sporadic Alzheimer's disease (AD).

The present study was designed to investigate the possible neuroprotective effect of p,p′-methoxyl-diphenyl diselenide [(MeOPhSe 2] in a model of sporadic dementia of Alzheimer's type (SDAT) induced by intracerebroventricular (i.c.v).

Such findings are quite consistent with an oligogenic model of sporadic epilepsy (Dibbens et al. 2007).

AR2 mice provide a mechanistic mouse model of sporadic ALS (Hideyama et al, 2010; Yamashita et al, 2012a).

As a result, we have established a new mouse model of sporadic α-synucleinopathy using wild-type mice.

From this point of view, the generation of cystatin C-positive cytoplasmic aggregates in our monkeys might strengthen their pathological value as a model of sporadic ALS.