Sentence examples for models of signalling from inspiring English sources

The effort to discover how costs can constrain an "honest" correlation between observable signals and unobservable qualities within signallers is built on strategic models of signalling games, with many simplifying assumptions.

Kinship is central to models of signalling between relatives, for instance when broods of nestling birds beg and compete for food from their parents.

Furthermore, most computational models of signalling pathways relate to events in a 'typical' cell.

Here, we consider models of signalling though the erythropoietin receptor (EpoR), transduced by STAT5 (Fig. 4a) (Darnell, 1997; Horvath, 2000).

Linking models of signalling to transcriptional networks would allow to integrate proteomics and gene-expression data, but how to best achieve this is still an open question [ 55].

Previous studies have used kinetic models of signalling pathways to detect mismatches between models and observations (Eissing et al., 2004; Smieja et al., 2008), but this work is among very few that have used pathway modelling to guide experiments towards actually confirming a previously unknown phenomenon (Hua et al., 2005).

Knepper's lab builds models of signaling networks by identifying specific protein kinases and phosphatases.

http://code.google.com/p/netflux/ CellNOpt Free software for creating logic-based models of signaling networks.

www.cytoscape.org Computational modeling Netflux Modeling and simulation tool for construction of normalized-Hill models of signaling networks from user defined species interactions.

EGFR has been extensively studied over the past three decades, and several recent analyses have provided system-level views and models of signaling downstream of the receptor [27] [30].

Quantitative mathematical models of signaling pathways are needed for thorough understanding of signal flow.