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Placental mTORC1 signalling has been reported to be inhibited in human IUGR [ 12, 13] and animal models of restricted fetal growth, such as maternal nutrient restriction [ 10].
We created models of restricted vascular flow by permanently ligating mouse carotid arteries and injecting the mice with human MSCs (hMSCs) to determine their effects on vascular lesions.
In order to evaluate the hindrance effect on the drug's diffusions in the Rf-PEG micelle, we have first reviewed the theoretical models of restricted diffusion [ 9, 10, 13, 20, 22, 29].
To this purpose they can be linked to semantic networks (another model elaborated in a specific sector of artificial intelligence that is called "knowledge representation") and usefully employed to build logical models of restricted domains (Gruber 1993).
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Our theorem can be applied in the case where the model of restricted three-body problem is usually considered.
Results supported a model of restricted gene-flow within viral subpopulations in the thymus and other tissues (Figure 5).
Under a model of restricted dispersal, it is predicted that genetic and geographic distance are positively autocorrelated at short distance, and negatively correlated at long distance.
Moreover, a continuous dispersal model from the Levant is significantly more likely than a model of restricted gene flow between Mesolithic and Neolithic populations when distances of 500 km and 1000 km are assumed (see Table 2, right column).
Herein, we employed this model of restricted EBV latency to address whether the virus may likely interfere with the type I interferon (IFN) response in normal B cells persistently infected with EBV.
The results of the Dow-Cheverud tests (Table 2) mirror those of the partial Mantel tests in showing that the continuous dispersal models and the model of restricted gene flow between Mesolithic and Neolithic populations are significantly more likely than the null model (Table 2, left column).
However, in contrast to the inhibition of type I IFN signaling by the LMP-1 protein of EBV during the growth or Latency III program [10], we found no evidence of such an effect in this cell model of restricted EBV latency.
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