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Homology models of rat TREK-1b were created using Modeller (9v8) (Sali and Blundell, 1993) based on KvAP (1ORQ), KcsA (1K4C, 3F5W, 3F7V, 3F7Y, 3FB5, 3FB6, 3FB8), MthK (3LDC), Kv1 (2R9R), MLotiK (3BEH) and NaK (2AHY, 3E86).
Two and three dimensional models of rat barrel and somatosensory cortex were simulated.
All the synthesized compounds were tested using the in vitro models of rat aorta and guinea pig trachea rings pre-contracted with phenylephrine and carbachol, respectively.
The retinal expression and activation of caspases and the patterns of caspase-3-mediated APP processing in ocular hypertensive models of rat glaucoma were investigated.
In this study we describe profound differences in metabolic and cardiovascular changes in severe, long-term models of rat and murine sepsis.
For this purpose, we focused on meprinβ expression in healthy rat kidney and in two models of rat glomerular disease: passive Heymann nephritis (PHN), a rat model of human membranous nephropathy, and anti-Thy 1.1 mesangial proliferative nephritis [3], [40] [42].
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We imaged intraabdominal bleeding models of rats as a potential use of 18F-FDG-labeled RBC PET.
Safety and efficacy of candidate drugs tested in test tubes or experimental tumor models of rats or mice are usually evaluated and approved by FDA.
Reasons include different carrier frequencies and corresponding channel models of RATs, base station positioning, different interference situations and sensitivity to it.
In inflammatory models of rats, TENS was also shown to significantly reduce pain sensitivity of both pressure and heat [ 14, 15].
TRPV1 also has been shown to mediate both mechanical and thermal nociception in cancer models of rats and dogs [ 28, 45, 46].
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