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A variety of engineered viruses have been developed and tested in numerous preclinical models of pediatric cancers and initial trials in patients are underway.
Genetically engineered animal models of pediatric and adult cardiac disease have proven that, when used appropriately, these tools have the power to extend mere observation to the establishment of true causative proof.
Preclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials.
Preclinical xenograft models of pediatric sarcomas showed antitumor activity [ 123].
Results also suggest that new service delivery models of pediatric rehabilitation should include features to increase information sharing with families and among interdisciplinary rehabilitation team members.
Imetelstat, a phase 2 telomerase inhibitor, was used to elucidate the effect of telomerase inhibition on proliferation and tumorigenicity in established cell lines BXD-1425EPNN, R254), a primary TIC line (E520) and xenograft models of pediatric ependymoma.
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Home environmental assessments and interventions delivered via academic practice partnerships (APP) between clinics and schools of nursing may be a low or no cost delivery model of pediatric asthma care and professional education.
Here, we addressed causative links between abnormal metabolite accumulation, brain inflammation and disease marker expression in a mouse model of pediatric neurodegeneration accompanying lysosomal storage diseases.
Fourth, the study was conducted in the model of pediatric supracondylar humeral fractures.
An integrative model of pediatric medical traumatic stress (PMTS) guides the study [ 25].
In an animal model of pediatric defibrillation with "infant" and "child" piglets, biphasic were more effective than monophasic waveforms [ 29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com