Sentence examples for models of mutant from inspiring English sources
Functional studies in cellular and animal models of mutant alleles provide direct evidence for neuronal hyperexcitability as one cellular mechanism underlying headache or aura in FHM [9].
These new mouse models of mutant EGFR-dependent lung adenocarcinomas provide insight into clinical observations.
Molecular models of mutant enzymes were generated using SYBYL Tripos AssociatesSt . Louisis, MO).
Models of mutant proteins were constructed using SwissModel (http://swissmodel.expasy.org/) and superimposed with Swiss-Pdb Viewer Magic fit tool.
Several mouse models of mutant Kras-driven lung Carcinogenesis have been widely used to study the role of Kras in NSCLC in vivo.
Animal models of mutant TP53 are invaluable for basic cancer research, the development of cancer therapeutics and screening compounds for carcinogenicity potential.
Structural models of mutants generated using the SwissPdb Viewer using BSX (PDB id-2FGL) as a parent molecule are shown in Figures 1D J.
Models of mutant-frequency changes over time are either deterministic or stochastic (Rouzine et al. 2001).
Computational modeling of mutant protein structures when compared to WT kinesin showed substantial differences in conformational flexibility and ATP-binding efficiency.
Thus, altogether, the measurement of the stability of its mutant forms provide evidence that GAN mutations confer instability of Gigaxonin in patients, and this notion is corroborated by the homology modeling of mutant locations.
Deletion of HDAC6 in a mouse model of mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis is also neuroprotective, as reflected by the extended life span of mice and increased motor axon integrity [ 48].
