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When JNK was inappropriately activated with endurance exercise in models of low response to aerobic capacity, endurance adaptations were impaired16.
Thus, using these innovative genetic models of low and high adaptive response, we hypothesized that JNK activation during exercise is a negative regulator of endurance adaptations in muscle.
In fact, we first discovered a potential JNK/SMAD signaling axis in samples taken following acute treadmill running exercise in our previous investigation of animal models of low and high adaptive response to endurance training16.
In rodent models of low adaptive response to endurance exercise, activation of JNK signaling with endurance exercise was associated with increased risk factors for chronic metabolic disease, including glucose intolerance and increased adiposity16.
The paper first establishes an analytical perspective, in terms of normative models of low carbon urban development and the specificities of Turkish urbanisation processes.
As detailed models of such processes turn out to be very complicated, POD is an attractive way to obtain reduced models of low order.
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We need to assist developing countries define new models of low-carbon, climate-resilient development.
Testing Models of Low-Frequency Variability (with Ulrich Müller), Econometrica Vol. 76, No. 5, September 2008, pp 979-1016.
These results provide some support for the evolutionary sequence-embedded protostar --> T Tauri star with a circumstellar disk --> T Tauri star without a circumstellar disk-currently envisioned in standard models of low-mass star formation.
Many of these vaccines have been tested for immunogenicity and protective efficacy in mouse and guinea pig models of low-dose pulmonary tuberculosis.
A typical approach in existing research on activity detection is to construct sequence-based models of low-level activity features based on the order of object usage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com