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Both levofloxacin and moxifloxacin have also proved effective in animal models of infective endocarditis [ 35, 36] and in anecdotal human cases [ 37, 38].
In murine models of bacteremia and in in vitro and rabbit models of infective endocarditis, telavancin demonstrated greater efficacy than vancomycin and similar or greater efficacy than daptomycin.
In several rabbit models of infective endocarditis, telavancin was more effective than vancomycin against most of the vancomycin-susceptible and VISA strains that were tested [ 35, 36].
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O21 Brain lesion spectrum characterization in an experimental model of infective endocarditis.
The in vivo binding of 67Ga-P04087 to phosphatidylserine was evaluated in a rat model of infective endocarditis.
We evaluated the in vivo binding of 67Ga-P04087 to PS in a rat model of infective endocarditis.
Therefore, our work showed that although successful in targeting PS expressed by activated platelets in the rat model of infective endocarditis (autoradiography), the contrast of the signal provided by Ga-P04087 was not sufficient to be detected in vivo.
This prophage encodes genes homologous to platelet-binding protein B (PblB) and an endolysin, both of which are required for the virulence of Streptococcus mitis in an animal model of infective endocarditis [33].
First, a deeper corelation is required to be established between its anti-inflammatory and anti-infective reactions through the in vivo models of infections.
In the other study, both telavancin and vancomycin demonstrated efficacy in the rabbit model of VISA infective endocarditis.
For instance, in the multivariable model, the main effect of "Infective Stage" in the model that also includes the interaction " Giardia Dose by Infective Stage" corresponded to a difference between cysts and trophozoites at a mean dose.
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