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Whether EA affects experimental itch in rat models of immunologic or neuronal damages, however, is unknown.
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This paper describes a model of the immunologic response of latent viruses and a donor kidney in a renal transplant recipient.
Activation of these counterregulatory systems has been shown to decrease inflammation, cell proliferation, and collagen deposition [ 21, 23] and improve healing in experimental models of the cardiovascular, renal, immunologic, and neurologic systems [ 24].
Progression of vaccine candidates to efficacy trials against TB disease rests on demonstration of safety and immunogenicity in target populations and protection against challenge in preclinical models, but immunologic correlates of protection are unknown, and animal models may not be predictive of results in humans.
B cells have been shown in murine models of leishmaniasis to contribute to immunologic regulation through production of cytokines and immunoglobulins and as a result of antigen presentation [ 22- 29].
28 The immunologic and glutamatergic models of BD are complementary because a proinflammatory state is one potential cause of excitotoxicity.
Lines of evidence have indicated that there are two types of immunologic responses in the human body and in animal models: T helper 1 (Th1 -based and Th1 -based (Th2)-bandd responses.
[12] Antibodies to M2e are protective in animal models, [4], [5] but there are no clinical studies testing the efficacy of M2e or any estimates of immunologic correlates of protection.
A decreased odds of immunologic failure was not significantly associated with any predictor in the univariate or multivariate regression models (Table 4).
Mucosal surfaces are rich of immunologic organs, thus all mucosal sites are theoretically able to be used as vaccinated routes.
Effective and safe treatment of immunologic diseases remains a challenging goal because of the complex, context-dependent function of numerous immunologic components.
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