Sentence examples for models of headache from inspiring English sources

However, little is known about the putative effect of melatonin in experimental models of headache [26].

Human models of headache may contribute to understanding of prostaglandins' role in migraine pathogenesis.

It is challenging, but clinically relevant, to identify patients at risk of developing MOH and therefore studies developing predictive models of headache chronification are important [50].

As Lifting The Burden considers models of headache service delivery and organization, and endeavours to make evidence-driven recommendations for change [17], one clear principle is that most headache management belongs in primary care.

While animal models of headache have been able to recreate migraine symptoms, including tactile sensitivity, modeling headache induction is still elusive.

Animal models of headache recreate the tactile sensitivity associated with headache but the mechanism of headache induction remains elusive [4], [5].

A human PGE2 model of headache has been developed and has demonstrated that PGE2 induces dilatation of cranial arteries and causes headache in healthy subjects [13].

To our knowledge, this is the first study where a potent and selective EP4 receptor antagonist, BGC20-1531, has been tested in a human model of headache.

Another alternative conceptual approach, the "severity model" of headache, considers a continuum of headache ranging from mild to severe forms with specific headache subtypes distinguished by level of severity rather than unique constellations of symptoms [30].

Using a human Prostaglandin E2 (PGE2) model of headache, we examined whether a novel potent and selective EP4 receptor antagonist, BGC20-1531, may prevent headache and dilatation of the middle cerebral (MCA) and superficial temporal artery (STA).

Table 3 Hierarchical model of headache type in child, psychiatric comorbidity in child, psychiatric disorders in parents and frequency (1 3/month = 1; 1/week = 2; >4/month = 3) (N = 198) Headache type in child Psychiatric comorbidity in child Psychiatric disorders in parents FREQ Obs.