Sentence examples for models of fragile from inspiring English sources
Galloway, J. N. et al. CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome.
Giving access to 3-D models of fragile archaeological remains through a seamless database improves students' learning experience but also can help researchers working at remote sites if they need a fast reference point, Seetah said.
In previous studies using mouse models of fragile X, Bear and others discovered that the loss of this gene results in exaggerated protein synthesis at synapses, the specialized sites of communication between neurons.
For instance, increased numbers of dendritic spines, which also appear longer and thinner than normal, were described in patients with Fragile X syndrome and were subsequently confirmed in mouse models of Fragile X syndrome [3].
It also addresses shortcomings in the current mouse models of Fragile X spectrum disorders.
As mentioned earlier, there are excellent mouse models of Fragile X, and there are now drugs that inhibit mGluR5.
Altered PAK signaling due to mutations in the PAK3 gene has been linked to patients with mental retardation, and PAK signaling is additionally implicated in models of fragile-X syndrome and schizophrenia (Chen et al., 2010; Hayashi et al., 2007; Hayashi-Takagi et al., 2014), making it an important molecule in the synaptic pathology of psychiatric disorders.
Evidence for social anxiety and impaired social cognition in a mouse model of Fragile X syndrome.
A mouse model of fragile X syndrome exhibits heightened arousal and/or emotion following errors or reversal of contingencies.
Suvrathan, A., Hoeffer, C.A., Wong, H., Klann, E. & Chattarji, S. Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.
Moon, J., Beaudin, A. E., Verosky, S., Driscoll, L. L., Weiskopf, M., Levitsky, D. A., et al. Attentional dysfunction, impulsivity, and resistance to change in a mouse model of fragile X syndrome.
