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Overall, these additional research directions are consistent with both investigation of exposures during pregnancy and models of exposures over the life-course that influence reproductive potential [21].
While it is difficult to develop exposure and toxicological models which are representative of a decades- or centuries-long SRM deployment, these efforts are critical to ensure that reasonable, validated models of exposures and human health impacts are available prior to any SRM deployment.
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Animal models of exposure are valuable for assessing potential toxicity and adverse health effects.
We use numerical models of exposure and burial as well as Monte Carlo simulations to constrain glacial chronology and infer process in this Arctic region dominated by cold-based ice.
We have replicated previous reports of an increased risk using conventional models of exposure.
In the present study we compared the results of proximity and LUR models of exposure to truck and bus traffic.
Future research, incorporating new and better models of exposure, should include segregation as a key factor in the analysis.
For categorical models of exposure to PFOA or PFOS, we assigned participants to four exposure categories based on distributions in the study population as a whole.
Findings were similar for separate models of exposure to PM ≤ 10 µm in diameter and PM between 2.5 and 10 µm in diameter and for copollutant models.
Adverse effects of cadmium on kidney and bone have been observed in environmentally exposed populations at frequencies higher than those predicted from models of exposure.
In general, we note that J-shaped or U-shaped models of exposure-risk result in substantial changes in the nature of seasonally-generated time series.
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