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Animal models of exposure are valuable for assessing potential toxicity and adverse health effects.
We use numerical models of exposure and burial as well as Monte Carlo simulations to constrain glacial chronology and infer process in this Arctic region dominated by cold-based ice.
We have replicated previous reports of an increased risk using conventional models of exposure.
In the present study we compared the results of proximity and LUR models of exposure to truck and bus traffic.
Future research, incorporating new and better models of exposure, should include segregation as a key factor in the analysis.
Findings were similar for separate models of exposure to PM ≤ 10 µm in diameter and PM between 2.5 and 10 µm in diameter and for copollutant models.
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Overall, these additional research directions are consistent with both investigation of exposures during pregnancy and models of exposures over the life-course that influence reproductive potential [21].
In general, we note that J-shaped or U-shaped models of exposure-risk result in substantial changes in the nature of seasonally-generated time series.
The raw data were analysed using Monte Carlo simulation and a European Statistical Population Model of exposure was constructed.
This study was carried out by European cosmetic manufacturers acting within the trade association Colipa, with the aim to construct a probabilistic European population model of exposure.
Furthermore, the State of California recently proposed reducing the lead MADL to 0.2 μg/day based on modeling of exposure levels that would result in maximum blood lead levels of 15 μg/dL (Cal/EPA 2015a; Cal/EPA 2015b).
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