Exact(2)
Due to the complexity, many models of epidermal development have focused on specific topics such as wound healing [ 70, 71], pathogenesis [ 72, 73], proliferation [ 74, 75], barrier function [ 76, 77] and homeostasis [ 42, 78].
Since the elaboration of in vitro skin models has arisen as an elegant response to the requests of activists wishing to ban the use of laboratory animals, the first attitude has been to create in different institutions or companies different models of epidermal cell cultures, each research group claiming that its own model was certainly the best for very specific reasons.
Similar(58)
In summary, in this study we describe a novel computational model of epidermal wound healing, based on previously published experimental work both at the cellular and sub-cellular levels, enabling hypotheses to be readily generated and tested.
(C and F ) Surface model of epidermal wall only with anticlinal walls replaced by boundary condition.
In this article, our goal is not to provide a complete validated model of epidermal development.
Thus, our results show that this in vitro differentiation model of epidermal keratinocytes recapitulates the epidermal stratification process.
In the second part, we describe a set of data-parallel algorithms to implement the model of epidermal development on GPUs.
We construct a 3D model of epidermal development and provide a set of GPU algorithms that executes significantly faster than sequential central processing unit (CPU) code.
Here we establish an adult Drosophila model of epidermal aging in a search for early healthspan biomarkers and the genes that regulate them.
In summary, although this model has been used the most frequently, notably as revealed by a number of citations over 2000 since its publication, the first model of epidermal keratinocyte exhibits limitations for several studies of human keratinocytes.
In the first, we define an integrated model of epidermal development that includes numerous methods, and this model will serve as a case study demonstrating the use of parallel technology for simulation.
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