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The application of models of diet breadth and patch-choice suggests that southern Iberia may not have had the large and medium game to easily support human consumer demand.
Our results confirm that optimal foraging models of diet composition developed to describe the ecological consequences of predator foraging decisions accurately describe the ecological dynamics of bacteriophage populations in laboratory microcosms.
Models of diet induced obesity (DIO) have been utilized to investigate immune responses to bacterial infections; however, the majority examine short-term effects [ 14].
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However, as an early step in translational research, many researchers are turning to models of diet-induced obesity.
Our results suggest that the dietary FA content and composition may be a primary determinant of diastolic, but not systolic, dysfunction in animal models of diet-induced obesity.
Differences in experimental protocol, which may deploy a single obligatory solid diet, a choice of solid diets, or liquid/solid combinations, and which may or may not allow a preferred macronutrient composition to be selected, mean that different models of diet-induced obesity achieve that obesity by different routes.
In several models of diet-induced insulin resistance, triglyceride accumulation is observed in muscle and liver.
We demonstrate that dietary KAA fortification prevented hepatic steatosis in mouse models of diet-induced obesity (DIO).
Mouse models of diet-induced obesity are considered to be relevant to the study of human obesity.
Considerable advance in this field was provided by the recent demonstration of the activation of an inflammatory response in the hypothalamus of animal models of diet-induced obesity [3], [5], [18], [19].
In summary, we show that dietary amino acid manipulation, in which protein is partially replaced by free ketogenic essential amino acids, can modulate metabolic alterations and prevent hepatic steatosis in mice models of diet-induced obesity.
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