Sentence examples for models of destructive from inspiring English sources

These cells are localized at the interphase of inflammatory tissue and bone, and are found in all animal models of destructive arthritis as well as in human RA [ 10- 13].

Overexpression of NOG rendered the cartilage more vulnerable in two mouse models of destructive arthritis (methylated BSA and CIA) [ 23] and inhibited the onset and progression of remodeling arthritis [ 8].

BMP2 stimulates proteoglycan synthesis in normal knees but cannot do this in a model of destructive arthritis [ 36].

This is an example of destructive interference.

John Belushi and Chris Farley powered through their brief lives in a bloated whirl and became models of self-destructive hedonism.

Astrophysicists studying the unstable "stellar monster" Eta Carinae have revealed new details and a 3D model of the destructive maelstrom at its heart.

So far, important insights into the mechanisms of RA-related destruction of cartilage have already been obtained from several animal models of arthritis, including destructive arthritis induced by various antigens, transgenic and mutation models and immunodeficient mice [ 12- 16].

According to the most familiar model of self-destructive addictive behavior, such behavior results from cravings that limit "the scope for volitional control of behavior" and can in some cases be irresistible, "overwhelm[ing] decision making altogether" (Loewenstein 1999, 235 6).

As the experimental model for destructive arthritis we chose mice that are transgenic for human tumor necrosis factor (hTNFtg), since these mice develop a destructive arthritis closely mimicking human RA [ 16] and their disease is based on overexpression of TNF, which is centrally involved in joint inflammation and arthritic bone loss.

Jenkins et al. [12] combined thousands of allometric models that performed destructive sampling of trees, and simplified them to just 10 models for general applicability.

This review describes the role of IL-17 in the pathogenesis of destructive arthritis with a major focus on studies in vivo in arthritis models.