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One obstacle to investigating the actions and roles of ERβ in neurons is the lack of cell based models.
A dynamic model for a finite volume of cell based on physical principles is built in the form of a nonlinear state-space model to investigate dynamic behaviors of tubular solid oxide fuel cell (SOFC) and develop a control relevant model for further control studies.
We have set out to devise a user-friendly generic platform, GemCell, for Generic Executable Modeling of Cells, based on whole, functioning cells.
AKD did all the molecular modeling studies and contributed to the development of cell based enzyme linked immunosorbent assays.
For example, to keep on with the same example above, one can decide to model the immune system response against a specific pathogen ignoring the specific type of cells and their properties and modeling the global effect of population of cells, based on whole-cell experimental recordings.
Experimental results are compared to a computational fluid dynamics (CFD) model of the cell, based only on turbulence characteristics.
More than 20 years ago, we introduced an alternative model of the cell based on tensegrity architecture which proposes that isometric tension in the cytoskeleton is critical for cell shape stability.
Our transcript profiling experiments identified a number of transcription factors that showed reduced expression in response to a loss of Prlr, but profiling of a cell based model of positive Prl action identified the ets transcription factor Elf5 [ 47].
Rao et al. have presented a modeling of a solar cell based on silicon diffraction grating [2].
A model of the symbiont cell based on functional predictions is presented in Figure 11 (see Additional file 3: Table S3 for the list of the corresponding gene products).
Retired breeder rabbits have been used for models of cell-based treatment for acute myocardial infarction and seem to be a reasonable model for human disease [ 132- 134].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com