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So much for mouse models of autism.
Silverman, J. L., Yang, M., Lord, C. & Crawley, J. N. Behavioural phenotyping assays for mouse models of autism.
Finally, we will highlight the huge potential impact of newly generated rat knockout models of autism.
Developmental dysfunction in peripheral somatosensory neurons causes altered responses to tactile stimuli and other behavioural deficits in mouse models of autism spectrum disorder.
A detailed study of four mouse models of autism challenges the most common assumption about what goes wrong in brain circuits to cause disease symptoms.
Cope, Elise C, et al. "Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism".
Similar(15)
Further, it has been shown that in murine models of autism-like disorders, the most conspicuous phenotype is an increase in programmed cell death in the developing cerebellum.
Rubenstein, J.L. & Merzenich, M.M. Model of autism: increased ratio of excitation/inhibition in key neural systems.
A specific amygdala circuit underlies social learning of fear, and targeted activation normalizes behavior in a rodent model of autism.
Rubenstein, J. L. R. & Merzenich, M. M. Model of autism: increased ratio of excitation/inhibition in key neural systems.
Nakasato, A. et al. Swim stress exaggerates the hyperactive mesocortical dopamine system in a rodent model of autism.
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