Effects of chronic fluoxetine in animal models of anxiety and depression.
However, there are very few reports describing the behavior of gerbils in traditional models of anxiety.
Noninteractive effects of diazepam and amygdaloid lesions in two animal models of anxiety.
However, to date, there are few reports describing the behavior of gerbils in traditional models of anxiety.
Consequently, it has proven difficult to test these agents in traditional rat and mouse models of anxiety and depression.
Therefore, it is difficult to assess the effects of many NK1 antagonists in traditional rat and mouse models of anxiety.
There are few reports, however, describing the behavior of gerbils in traditional in-vivo models of anxiety.
Adult hippocampal neurogenesis has been implicated in animal models of anxiety and depression and behavioral effects of antidepressants.
There are NK1 antagonists that have comparable affinity at rat and human NK1 receptors and have been tested in traditional models of anxiety and depression.
This data suggests that MK-869 and CP-122,721 may be suitable for testing in traditional rat models of anxiety and depression.
Thus, although SP and senktide are similar in activating 5-HT neurons, they differ in their overall effect in preclinical models of anxiety.
