Sentence examples for models of allergy from inspiring English sources

Elevated IL-9 production and Th9 differentiation have been demonstrated in mouse models of allergy and melanoma [ 54, 55].

Passive cutaneous anaphylaxis (PCA) is the gold standard method to measure allergen-specific IgE antibody levels in mouse models of allergy.

Prior to clinical development of the T cell epitope peptide therapies, murine models of allergy were developed to validate the strategy and further explore mechanisms.

Impairment of immune tolerance has been shown to augment disease in various models of allergy and/or autoimmunity, including diabetes onset in NOD mice [ 18, 19], collagen-induced arthritis [ 20, 21], and experimental colitis [ 22].

Different strains of bifidobacteria were shown to have profound effects on dendritic cells, macrophage, and T cells of healthy humans and in animals models of allergy or intestinal inflammation [ 42– 42].

The effects of LPS on Th2 responses in animal models of allergy remain uncertain as LPS has been demonstrated to increase (Delayre-Orthez et al., 2004), decrease (Gerhold et al., 2002; Rodríguez et al., 2003; Komlósi et al., 2006) and not alter (Murakami et al., 2007) them.

Vaccines using genetically modified LAB as mucosal antigen delivery vehicles have been tested in mouse models of allergies to house dust mites [ 27– 29], eggs [ 30], birch pollen [ 31], Japanese cedar pollen [ 32], and cow's milk [ 33].

Given their regulatory effects, it is not surprising that 'old friends' can be shown to drive immunoregulation, and to block or treat pathophysiology in models of allergies, autoimmune disease and IBD 29, 38, 39.

A similar correlation between certain allergic responses and increased IFN-γ expression has been reported in human clinical studies of allergy; this pig model of allergy may be indicative of potential probiotic modulation of allergic lung disease in humans.

Using this pig model of allergy we demonstrated the ability to induce allergic manifestations of immediate skin hypersensitivity and allergic lung disease in pigs, as well as a reduction in the severity of both of these allergic manifestations via probiotic intervention.

In this swine model of allergy, the allergic response was induced by immunizing pigs with an extract from the roundworm Ascaris suum containing allergens known to elicit strong Th2 responses [23] that had been mixed with alum, an adjuvant classically used to further enhance the intensity of Th2 responses.