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Crystal, A. S. et al. Patient-derived models of acquired resistance can identify effective drug combinations for cancer.
Crystal, A.S. et al. Patient-derived mofels of acquired resistance can identify effective drug combinations for cancer.
Morris, E. J. et al. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Elucidating the mechanisms supporting survival of central auditory nerve synapses in models of acquired deafness may reveal new opportunities for therapeutic intervention.
The lack of clinically relevant models of acquired epileptogenesis, that can be used to screen for better drugs and to optimize the design of clinical trials, has hampered progress.
Indeed, inhibition or down-regulation of ER reduces tumor growth in preclinical models of acquired endocrine resistance, and many patients with recurrent ER+ breast tumors progressing on one type of ER-targeted treatment still benefit from sequential endocrine treatments that target ER by a different mechanism.
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Therefore, the current study was conducted in a rat pilocarpine model of acquired epilepsy.
Sirac, C. et al. Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome.
Weissberg, I. et al. Albumin induces excitatory synaptogenesis through astrocytic TGF-beta/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction.
This study was designed to investigate histopathologically the therapeutic efficacy of lead peptide RIP YSPWTNF-NH2 in the subcutaneous air sac murine model of acquired S. aureus sepsis.
In a porcine model of acquired lymphedema, animals were treated with BioBridge scaffolds, alone or in conjunction with autologous lymph node transfer as a source of endogenous lymphatic growth factor.
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