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Knots in polypeptide chains are often difficult to detect simply by visual inspection, as evidenced by the fact that the assessors still accepted several knotted CASP6 comparative modeling models, most likely because it was not visually apparent that these models contained knots (Khatib et al., 2006).
Noticeable but still minor differences arise only for the colder models, most likely due to the different equation of state used in our simulations.
The data of the present study are in conflict with previously published data from healthy animal models, most likely as a result of ongoing resuscitation including noradrenaline treatment or intrinsic pathophysiologic processes of the pre-existing atherosclerosis.
RNAi therapy using lentiviral delivery exhibited marginal efficacy in ameliorating disease and pathology in previous in vivo prion disease models, most likely because direct ic injection limited viral transduction to cells immediately adjacent to the injection site [12], [13].
The pattern of these associations differed from that in the single-exposure models, most likely owing to differences in missing data patterns across these analyses.
Implanted animal tumor models most likely represent clinical end-stage disease and may not necessarily recapitulate clinical behavior seen during tumor development in humans.
Similar(48)
Every social media company, like Twitter and Instagram, a mobile photo-sharing application, and Foursquare, a location-based service, will have to introduce a coherent business model — most likely one that will make use of what it knows about the people who have access to and use its service.
These results indicate that LASSBio-965 can attenuate the pulmonary arterial hypertension in an animal model most likely through the nonselective inhibition of phosphodiesterases 3, 4, and 5.
While the startup is still tinkering with its business model (most likely based on affiliation and sponsored links), it would definitely make sense to offer discounts to users with a certain number of points.
In contrast, Model 3 received an overwhelming majority of the second preference allocations in the morning but there was a noticeable drop in the afternoon; in the afternoon session Model 3 emerged as the model most likely to be ranked first preference.
"The treatment model most likely to deliver the best outcomes for an individual is one decided between the individual and their doctor or service provider," says the commission, "free from political interference or coercion".
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