Sentence examples for models mimicking the from inspiring English sources

Thus, in order to identify an efficient anti-fibrogenic compound, novel in-vitro models mimicking the interplay between pro-fibrogenic cell populations, immune cells and, importantly, the extracellular matrix need to be developed.

The limitation of the static environment in Boyden devices has been overcome both by the use of parallel-plate flow chambers and by custom models mimicking the in vivo conditions, along with widespread microfluidic approaches to in vitro modeling.

This GI safety is observed when the drugs are tested in animal models mimicking the co-morbidities in humans that are associated with increased susceptibility to GI ulceration, including hypertension, diabetes, obesity and old age.

Here, we discuss how 3D microfluidic tumour models mimicking the tumour microenvironment could help in testing T cell immunotherapies by assessing engineered T cells and identifying combinatorial therapy to improve therapeutic efficacy.

For better reservoir characterisation, six statistical models mimicking the log log pressure derivative approach are derived using the steps below; First, the 1st pressure and time differencing are obtained: begin{aligned} Delta P_{t} = P_{0} - P_{i} hfill Delta t_{t} = t_{i + 1} - t_{i} hfill end{aligned} (4).

In animal models mimicking the clinical situation of mechanical ventilation and oxygen therapy in the saccular stage of lung development, the fibroblasts and elastic fibers are diffusely scattered in the mesenchyme and are no longer located at the top of the secondary crests where they normally contribute to further lung growth [20, 21].

Such models mimic the polar forms of the human disease and are correlated with an elevated production of IgG1 and IgG2b antibodies [24].

Therefore, the models mimic the symptomology and management profile of the disease.

However, it is unclear how well these models mimic the metastatic process in humans.

Although rodent models mimic the protective effects of parity in women, significant differences exist.

Since the latter models mimic the limit in which no back diffusion is present, they easily overestimate the efficiency.