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However, this problem is inherent to the use of other "nonhuman" models; mice, for instance, also show different activity for inducible NO synthase (iNOS -related NO release [18, 19].
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(a,b) Plasma SCFA levels of AD model mice for acetate (a) and for propionate and butylate (b).
We found progressive deterioration in SMA model mice for most measures studied particularly body weight, survival, body temperature and motor function with differences appearing as early as P3.
We studied, over time, the spinal cords of ADAR2-knockout mice, which are the mechanistic model mice for sporadic ALS, using homozygous ADAR2flox/flox/VAChT-Cre.Fast (AR2), homozygous ADAR2flox/flox/VAChT-Cre.Slow (AR2Slow), and heterozygous ADAR2flox/+/VAChT-Cre.Fast (AR2H) mice.
To further investigate molecular pathogenesis and to explore therapeutic strategies for dystroglycanopathy, we generated several model mice for FCMD.
It should be noted that the reductions of VP and OT are also observed in brains of model mice for another polyglutamine disease, dentatorubral-pallidoluysian atrophy (DRPLA) (48).
In this regard, the chromosome-engineered mouse described here is a model mouse for autism that parallels both phenotypic and genotypic aspects of the human disease.
In the MRLlpr/lpr lupus model, mice deficient for MyD88 failed to produce DNA autoantibodies [ 40].
Similar cognitive deficits have been described for AD model mice.
The S value was determined for the cell nuclei in species-specific thyroid follicle models for mouse, rat and man for different spatial distributions of radioiodine.
There are 15 mice in the control group or tumor group (totally 30 C57BL/6 mice for melanoma mouse model, another 30 DBA/2 mice for lung cancer mouse model).
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