But like may other radical new business models it requires a systemic change, which no single business or organisation can bring about on their own.
Depending on a teaching, recognizing model which is provided by hidden Markov models, it requires to form appropriate coded observation vectors.
Because HD4AR relies on 3D point cloud models, it requires that users first take overlapping photos of the target scene to produce the initial 3D point cloud used for localization.
Although colonic tumorigenesis can be increased in mouse models, it requires further genetic manipulation, carcinogenic treatments, or chemical or physical abrasion (Byun et al., 2014; Grill et al., 2014; Hinoi et al., 2007; Hung et al., 2010; Møllersen et al., 2004; Paul Olson et al., 2014; Ritchie et al., 2009; Suzui et al., 2002).
As shown in the present study, L. infantum also caused a proliferation of NK cells (Fig. 2A), but unlike to the MCMV model it required IL-15 and did not lead to a measurable expansion and accumulation of NK cells in the spleen (Fig. 2B).
Although the ODA seems to be more suitable for modeling, it requires the knowledge of the spatial variations of the transport parameters.
It has been reported that Carreau equation is more powerful in providing a better fit to the viscosity/shear rate data (Bird and Hassager 1987; Chauveteau 1982); however, compared to the two parameters in power law model, it requires four.
Further, being based on a parameterized network evolution model, it requires the estimation of numerous model parameters.
Comparing to BLM-NII, RF and CS-PD model, it require crystal structure to extract local information (binding site) in FIM, which hinder the applying of FIM sometimes.
To be applied to our ODE model, it requires expanding each term of the Michaelis-Menten kinetics into corresponding elementary reactions, which will add to significant computational demand especially when we intend to simulate more than one hundred single cells.
