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In such circumstances the inferred locus will always contain the critical voxel, though of course the centre of the cluster of voxels crossing the significance threshold could be, and in our models is, located elsewhere, distorting the inference.
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Attempts to manually align these gene models failed for 15 of them, three of these gene models are located in contig breakpoints, 13 of them mapped to multiple locations and the remainder can be aligned but failed one of the quality control steps during RATT transfer.
While Paul looks at his computer monitor to see where the various models are located, Subreena Jadhav has been on the telephone to Japan.
Because these two models are located in different coordinate systems, an optimal spatial transformation matrix is necessary.
Using the closed-loop stability condition the minimum number of models is found and the models are located in a space of an unknown parameter.
All the features (regions of interest) selected by the best models were located in prefrontal cortex (PFC), anterior cingulate cortex, and parietal cortex.
However, system models are located far away from where the data is generated which adds complexity for cross-domain communications and resource management.
In addition, none of the genetic loci for these models are located on chromosome 4.
However, it should also be noted that the GABBR2 SNPs included in the interaction models are located in the intronic regions among exons encoding transmembrane and cytoplasmic domains of the GABAB2 subunit.
The four sites with significant evidence of dN/dS>1 in both the M2 and M8 models are located in the extracellular (EC) loops of this protein, one S55 in EC1 and three S333, M334 and F339 in EC4.
The SCS QTL identified by the STLDLA and STLD models was located at 39.8 cM (Tables 1 and 2).
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