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Tumorigenesis in c-Myc transgenic mouse models is accelerated if combined with other anti-apoptosis genetic alterations, such as overexpression of Bcl-2 [51] or Bmi1 [52], or disrupting the ARF-MDM2-p53 pathway [53].
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Since the relaxation dynamics of the coarse-grained models are accelerated by the smoothed potentials, single numerical factors are introduced to rescale the time scale of the coarse-grained models, respectively.
Tumorigenesis in this model is accelerated by loss of p53 and hence appeared most suitable to study the tumor suppressor potential of the PIDDosome.
Progress in scientific understanding and computational modeling are accelerating researchers' ability to predict the structure and properties of new materials before actually making them, Phillips said.
We report the first in vivo imaging study of VEGFR prevalence in atherosclerotic plaques in diabetic vs. non-diabetic atherosclerosis-prone ApoE−/− mice, a model where atherosclerosis is accelerated by diabetes.
Here we demonstrate that the POKO mouse is a model of renal disease that is accelerated by high levels of glucose and lipid accumulation.
The important features in the experiments are captured by the model, i.e. the creep is accelerated by the moisture cycling and the mechano-sorptive effects are larger in compression than in tension.
Such two ZNN models can be accelerated to finite-time convergence to the time-varying theoretical pseudoinverse.
In conclusion, the healing of a closed fracture in a goat model can be accelerated by a single local administration of rhOP-1.
For the stronger damage conferred by myeloablative therapies the response of the hybrid model can be accelerated by an adaptation of the transition characteristics that makes them more sensitive to changing cell numbers.
Many of the parametric models such as Weibull are accelerated failure time models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com