Sentence examples for models injection of from inspiring English sources
In orthotopic glioma models injection of NSCs transduced with the gene for cytosine deaminase led to a strong reduction of tumor burden [ 1].
In the most common experimentally induced models, injection of adjuvant and various joint matrix components, such as collagen type II or proteoglycan aggrecan, causes autoimmune arthritis in susceptible inbred mouse strains [ 28, 29].
The seismic temporal increase is strongly correlated with the results of recent simulations, modelling injection of magmatic fluids in the Campi Flegrei hydrothermal system.
However, in our capsaicin model, injection of the trkB-IgG fusion protein (an inhibitor of BDNF function [64]) into the area of secondary hyperalgesia (10 µg/50 ul, 4 h prior to capsaicin injection) had no effect on pinprick pain thresholds compared to vehicle controls (data not shown).
In a similar series of experiments using the same rat ROP model, injection of anecortave acetate also reduced VEGF protein at one and two days post-oxygen exposure.
In this well characterized model, injection of the cytotoxin streptozotocin (STZ) results in a reduction in ß-cells and an increase in plasma glucose to diabetic levels [ 4].
In vitro F XIII caused a dose-dependent enhancement of array formation in a Matrigel tube formation model, while in a rabbit cornea model, injection of F XIII led to neovascularization [ 28].
In the DT-22 model, injection of 100,000 cells of each cell type failed to yield metastasis when tumours were excised at 1 cm and animals followed for a further 10 months.
In a different model, injection of DTA-1 8 days after the inoculation of BALB/c mice with a methylcholanthrene-induced fribrosarcoma produced tumour-specific immunity (Ko et al, 2005).
Mice were first subjected to malignant tumor inoculation by either subcutaneous (model of local tumor) or intravenous (metastatic model) injections of the MCA205 fibrosarcoma cell line.
In summary, animal models using injection of peptide into animal brain offer alternative approaches to the more thoroughly studied transgenic mouse models.
