Sentence examples for models including rodents from inspiring English sources

These robust cardiac differentiation methods have provided cells for cardiac drug testing in vitro4,11 and xenotransplantation of human PSC-derived cardiomyocytes (hPSC-CMs) in animal myocardial infarction (MI) models, including rodents, pigs, and nonhuman primates (NHPs 12,13,14.

A number of studies have demonstrated that CNTF is a potent neuroprotective factor for striatal MSNs in animal HD models, including rodents and primates.

In contrast, studies in animal models, including rodents and primates, clearly show that prenatal cocaine exposure has deleterious effects on the developing brain, affecting both cognitive functions and emotional responses [5], [6].

Methionine restriction (MetR) extends lifespan in animal models including rodents.

Indeed, AAV (adeno-associated virus -mediated gene therapy for inherited retinal disorders has been successful in a virus -mediatedal models, includingenedentherapyanine models oforeber congeninheritedretinalLCA) (15– 20), the CNGA3 andisorderseficiency mouse models (21, 22) and canine models of CNGB3 mutation/deficiency (23).

Firstly a decision on small or large animal model is required is necessary: small animal models include rodents such as mice, rats and rabbits; while large animal models include dogs, goats, sheep, pigs and horses.

Rapamycin analogues are currently used as chemotherapeutics [ 80] and rapamycin also increases life span in several model organisms, including rodents [ 76, 81- 86].

CR or intermittent fasting are known for their wide life-span-extending and health-improving effects that can be measured in an objective fashion in multiple model organisms including rodents and primates.

NAD+ levels also decline during aging in multiple models including worms, rodents and human tissue [17, 45, 67, 72].

Since AAV vectors have broad host ranges, our 'hit-and-run' antigen transduction system can be used to induce immunological beta cell injury in various animal species, including rodents, large animal models and non-human primates, with particular genetic backgrounds and ageing status.

In most cases, transmission of PrPsc has been proven in animal models including primates and rodents; this has established PrPsc as the transmissible agent of diseases [ 3- 5].