Sentence examples for models including prostate from inspiring English sources

Proteasome inhibition has been shown to be an effective anticancer therapy in many tumor models, including prostate cancer.

TAT-fusion proteins and peptides have been used to promote cell death in mouse cancer models including prostate, breast, leukemia, melanoma, and glioma [37].

After systemic administration in mice, fisetin has shown interesting antitumor activity in several cancer models, including prostate, teratocarcinoma and lung carcinoma [ 12, 13].

Zyflamend, a mixture containing extracts of ten herbs, has shown promise in a variety of preclinical cancer models, including prostate cancer.

Research has focused on the anticancer effect of allyl sulfides in culture and in vivo models, including prostate, lung, and colon cancers.

The development of inhibitors of HMTs and HDMs is less advanced than for DNMTs and HDACs; however, there are a number of inhibitors of these molecules that have now been investigated in cancer models, including prostate cancer.

For example, Deras et. al. reported that addition of PCA3 to a model including prostate volume, DRE result and PSA improved the discrimination of prostate cancer on biopsy from and AUC of 0.67 to 0.75[ 20.75[

Preclinical studies reveal potent Hsp90 inhibition and activity against a range of models including lung, prostate, colon, breast, melanoma and leukemia [ 13- 15].

5-Aza-2'-deoxycytidine (5-Aza-CdR), a nucleoside analog inhibitor of DNA methyltransferase (DNMT), has been used to reverse methylation and reactivate the expression of silenced genes [ 5]. 5-Aza-CdR was able to suppress the growth of various tumors in vitro, animal models, and clinical trials including prostate cancer [ 6- 9], hematopoietic malignancies [ 10, 11], and lung carcinoma [ 12].

Similarly to IL-2, IL-21 is expressed by activated CD4+ T-cells and has been described as having anti-tumor effects in mouse models for several different malignancies, including prostate cancer [ 13].

Here, the anti-cancer activity of Gamitrinib in TRAMP mice extends recent studies in xenograft models (Kang et al, 2009), including prostate cancer, where systemic administration of Gamitrinib-TPP (Kang et al, 2009) suppressed the growth of subcutaneous or bone-localised PC3 prostate tumours in immunocompromised mice (Kang et al, 2010).