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Use of such multifactorial models, including interactions, may pave the way to prediction of diabetic nephropathy and other complex genetic diseases in other populations.
We tested all possible models including interactions among explanatory environmental and genetic variables.
Poisson regression models including interactions were used to explore trends over time by socioeconomic deprivation and maternal age.
Models including interactions were not fit for MPA and VPA separately as the VPA models did not converge, so MVPA was used instead.
Nevertheless, an expanded examination of more complex models including interactions between gene expression and clinical information is warranted in future studies.
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We also ran regression models including interaction terms.
Linear regression with models including interaction and quadratic terms were capable of producing powerful predictive models.
The full models including interaction terms are presented in tables 4 and 5.
We also evaluated models including interaction terms for fiber type × covariate (p-value < 0.05 considered significant).
Models including interaction terms between occupation/smoking, occupation/alcohol or occupation/education did not show any significant interaction.
Additional models including interaction terms between migration background and language region or period showed no remarkable differences.
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