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With the exception of the Glinsky et al. 2004 Signature 1, all of the gene/probe models had significantly lower AUCs in the validation set compared to the training set. Figure 2F compares the training and validation set AUCs of each of the gene/probe models including clinical model C.
Therefore, in specific populations such as cardiac surgery, the use of prediction models including clinical risk factors is recommended.
By the use of multistate models in Cox proportional hazards models, we analysed the HR for re-employment, sickness absence and retirement in models including clinical as well as health-related variables.
In models including clinical variables and perchlorate or thiocyanate or nitrate concentrations, we found a significant positive association between each of the goitrogenic anions and urinary TSH and T4.
6 However, the association of CD226 and AFF3 variants with the anti-TNF response is weak, and the addition of these markers into predictive models including clinical variables has only a modest effect, increasing the r value from 15.7% to 17.0%.
Similar(55)
Models included clinical risk factors and a 40-SNP weighted genetic risk score.
To date, the major examination in studies of CIA mouse models includes clinical symptoms as well as radiographic and histological assessments of arthritis.
The C-index increased from 0.66 to 0.71 when adding BSI to a model including clinical stage, Gleason score and PSA.
The C-index increased from 0.66 to 0.71 (p = 0.006) when adding BSI to a model including clinical stage, Gleason score and PSA.
The added value of BSI was shown as an increase in C-index from 0.66 to 0.71 when adding BSI to a model including clinical T stage, Gleason score and PSA.
A clinical model including clinical variables only; 2).
Related(17)
models incorporating clinical
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models including several
model including clinical
models including subjects
models including cells
models including symptoms
models including studies
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