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The models included both fixed and random effects for the intercept and slope.
CLIMAP models included both a maximum and minimum model of glacial extent; the former was associated with a sea level decline at LGM of 163 meters while the minimum model predicted a sea level decline of 127 meters (Denton and Hughes 1981).
Since the pathological changes in these models included both a loss of the TH-positive neurons and a decrease in the TH expression in the lesioned side, we not only counted the number of TH-positive cells but also measured the integrated intensity of both sides of the VTA and SNc.
In addition, the initial linear regression models included CD4+ T cell count at visit 1, when evaluating the impact on HIV viral load, or HIV viral load at visit 1, when evaluating the impact on CD4+ T cell count, while the logistic regression models included both.
Unconditional models included both the matching and additional adjustment variables.
Models included both interventions and interaction term of interventions.
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The developed FE models include both material and geometric nonlinearities.
The plasma models include both particle-in-cell and fluid models.
Constitutive models including both concrete cracking and post-peak response of the materials were implemented.
With presence of uncertainties, the surrogate models include both mean and standard deviation components.
It is noteworthy that the design models include both a mathematical optimization model and a physical optimization model.
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