Sentence examples for models in normal from inspiring English sources

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However, more often than not, these drugs failed to behave "appropriately" in preclinical in vivo models, in normal individuals, or in patients, reflecting a lack of efficacy and/or intolerable adverse effects that could not be predicted by a reductionistic approach.

Similar(59)

In view of the scope of the current paper, it suffices to describe this agent-based model in normal language rather than in SDCPN language.

Finally, theoretical developments are validated through simulation results by means of a detailed model in normal operation and during an AC voltage sag.

To investigate the hypoalgesic effect of amplitude-modulated frequency during interferential current therapy using an experimentally induced mechanical pain model in normal subjects.

For in vivo imaging of Aβ plaques, the basic pharmacokinetic model in normal brains involves a high initial penetration of the agent, followed by facile clearance due to lack of a binding target.

According to our model, in normal conditions the first cell divisions occur at ∼2 days, when the DN cells, guided by CXCL12 gradients (Fig. 1B) reach the subcapsular zone.

Further studies will be needed to understand the relevance of this model in normal monocytopoiesis and AML.

According to this model, in normal scene perception, an external visual input activates a number of potentially seen visual object representations, which they called 'proto-objects'.

In this model, in normal cells, IGFBP-3 is induced by factors such as growth hormone (GH) and IGFs, and steady levels of expression are observed in some cells.

However, a recent model in normal individuals showed that peak expiratory flow was limited by mechanical properties of the lung (in accordance with the wave speed mechanism), and not by muscle strength [ 26].

These results provide greater support for the elite model instead of the stochastic model in normal tissues and support our suggestion of an elite model in cancer by which multipotent CSC are poised to become pluripotent stem cells in heterogeneous populations.

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