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There are several pathological, ethical and logistical challenges that limit the use of in vivo surgical models in humans.
Transcriptional regulation models in humans must therefore take into account both the gene density and long intergenic sequences.
Several studies have reported a significantly higher cytokine production in males [ 54, 55], using ex vivo models in humans [ 56- 59] and animals [ 60- 62].
Past studies using different loading models in humans and animals have demonstrated that loading stimulates bone formation while unloading decreases bone formation.
Adaptation to chronic stress has been observed in various stress models in humans as well as animals [ 38, 39], while an inability to adapt may result in diseased states.
The mechanical power of vertical jumping has been calculated from first principles and models in humans (Bosco et al., 1983; Nagano et al., 2005), and the costs of leaping similarly calculated for saltatory primates (Warren and Crompton, 1998).
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Trust management models in human-centric applications can enhance the security assurance.
First published in 1985, the HKB model of this coupled behavior is one of the most extensively tested quantitative models in human movement [49].
These data suggest that, differently from the animal models, in human patient SE cannot be considered a sufficient condition for epileptogenesis.
There are several microsimulation models in human medicine, and they can be either dynamic or static.
Although several animal lung injury models have been utilised, the relevance and applicability of these models in human ARDS remain uncertain.
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