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First published in 1985, the HKB model of this coupled behavior is one of the most extensively tested quantitative models in human movement [49].
These data suggest that, differently from the animal models, in human patient SE cannot be considered a sufficient condition for epileptogenesis.
There are several microsimulation models in human medicine, and they can be either dynamic or static.
First, hypercoagulability is associated with increased atherogenesis in experimental models; in human beings, markers of clotting activity are also linked to cardiovascular disease outcomes.
Although several animal lung injury models have been utilised, the relevance and applicability of these models in human ARDS remain uncertain.
To explain these findings Moore et al. (2009) proposed a form of optimal cue integration based on established models in human perception.
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Here, we review these advances and discuss the potential of this systems vaccinology approach in defining novel correlates of protection in clinical trials, and in infection-induced 'experimental challenge models' in humans.
Trust management models in human-centric applications can enhance the security assurance.
There are several pathological, ethical and logistical challenges that limit the use of in vivo surgical models in humans.
Transcriptional regulation models in humans must therefore take into account both the gene density and long intergenic sequences.
Several studies have reported a significantly higher cytokine production in males [ 54, 55], using ex vivo models in humans [ 56- 59] and animals [ 60- 62].
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