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The efficiency of housing, breeding, and handling rodents has made them the most widely used animal models in biomedical research.
This chapter discusses the conceptual basis and rationale for modeling, with particular emphasis on the role of dynamic computational and mathematical models in biomedical research.
Concerns about infectious diseases in fish used for research have risen along with the dramatic increase in the use of fish as models in biomedical research.
Fortunately, the advent of rapid, low-cost in vivo somatic modeling techniques (e.g. CRISPR), enhances the utility and impact of mouse models in biomedical research.
The rat was first domesticated for scientific research over 100 years ago and rapidly became one of the most important experimental animal models in biomedical sciences [1].
AGMs have provided useful animal models in biomedical research for many years [ 17, 42- 50].
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"The chimpanzee is no longer an essential model in biomedical research," he says.
The zebrafish is an established vertebrate-animal model in biomedical research.
The dog is an excellent model for studying human diseases, and the availability of canine ESCs would open new possibilities for this model in biomedical research.
The rat is an important animal model in biomedical research, but gene targeting technology is not established for this species.
The dog is an important model in biomedical research for several reasons.
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