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These models have utilised smaller amounts of data in comparison to NB models, mostly due to the computational expense of the SVM algorithm.

Likewise several models have utilised enzyme digestion of the extracellular matrix (summarised in reviews [ 4, 14].

Currently, most H. pylori vaccines in animal models have utilised whole-cell preparation of native or recombinant proteins from the bacterium, together with mucosal adjuvant.

Many experimental models have utilised either in vitro studies of isolated cell lines or animal and human studies where LPS is exposed to the circulation by parenteral injection.

Earlier studies in animal models have utilised either a single high dose or chronic intake of higher doses than those employed in the current study [ 36, 37].

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Previous crowd structure interaction modelling has utilised a continuous hydrodynamic crowd model.

Deep-learning models We have utilised three types of neural networks: one-dimensional (1D) convolutional neural networks (CNN), recurrent neural networks (RNN) and time-distributed dense (fully-connected) networks (TDD).

To date, the only other data, where cells within multicellular systems have been targeted with radiation demonstrating bystander responses, have utilised models containing one cell type (Bishayee et al, 1999, 2000).

This has prompted researchers to develop alternative models of care which have utilised different healthcare professionals in care delivery and/or shifted the focus of care from hospital to the community [ 4, 29, 30].

The authors note there are a number of models that could be used to guide the development of services in addition to the logic model framework that the research partnership have utilised in current example, such as Outcomes Star (MacKeith, 2011).

Moreover, we have utilised surrogate models to improve the efficiency of the design process.

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