Acute In vitro models have revealed a great deal of information about mechanisms underlying many types of epileptiform activity.
Several animal models have revealed that platelet-derived serotonin initiates liver regeneration after hepatectomy.
Our new tissue culture models have revealed virus-like particle arrays (at left) that correspond to isolated infectious brain particles of ~25nm.
Several studies using animal models have revealed an inverse relation between gluco-corticoid levels and hippocampus volumes.
In vivo studies in murine models have revealed that IL-8 produced by melanoma cells is involved in neutrophil activation and chemotaxis, which results in increased metastatic homing to the lung156.
Studies on ABCA12-deficient bioengineered models have revealed that lipid transport by ABCA12 is required for keratinocyte differentiation and epidermal morphogenesis.
These models have revealed a crucial role for dendritic cells not only during priming but also during reactivation of Th2 cells in asthma and rhinitis.
Physiological and behavioral studies in animal models have revealed that information from the different senses can be used synergistically to enhance the detection of objects and events.
Losses and gains in species diversity affect ecological stability1,2,3,4,5,6,7 and the sustainability of ecosystem functions and services8,9,10,11,12,13. Experiments and models have revealed positive, negative and no effects of diversity on individual components of stability, such as temporal variability, resistance and resilience2,3,6,11,12,14.
Earlier studies based on various tumor models have revealed an essential role of immune cells in controlling metastasis of breast tumors.
Our pre- and post-tectonic models have revealed the reasons for instability and the likely places where future failures may be located.
