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Over the years, these models have expanded our understanding of the pathogenesis of many neuropsychiatric disorders and neurodegenerative diseases.
We will examine how these models have expanded our understanding of PD pathogenesis and progression, as well as aided in identification of potential therapeutic targets in this disorder.
Similarly, while many existing student engagement conceptual models have expanded to include factors that influence student engagement, none highlight the overt role of technology in the engagement process (Kahu, 2013; Lam, Wong, Yang, & Yi, 2012; Nora, Barlow, & Crisp, 2005; Wimpenny & Savin-Baden, 2013; Zepke & Leach, 2010).
Theoretical models have expanded the functional explanation given to general sex differentiation in the dependence of fitness on date of birth (Daan et al. 1996; Pen et al. 1999).
Many of the most recent models have expanded this further by focusing on the evolution of multiple traits (for example growth, PMRNs, and reproductive investment and on less studied traits such as migration (Jørgensen et al. 2008a; Thériault et al. 2008; Miethe et al. 2009) and sex allocation in hermaphrodites (Sattar et al. 2006).
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In large part, work with other animal models has expanded upon studies in the dt rat and shown that primary dystonia is a multi-nodal network disorder associated with defective sensorimotor integration.
Pharmaceutical, chemical and high tech companies are among the biggest customers so far, but the focus on "methods of doing business" patents–essentially patented business models–has expanded Aurigin's potential customer base to the manufacturing and service industries as well.
The study of genes associated with infertility in rodent models has expanded the field of translational genetics in identifying the underlying cause of human infertility problems.
This whole area of statistical models has expanded very much during the last 10 15 years thanks to theoretical advancements as well as the development of suitable software.
Elite's model has expanded Braben's understanding of planet formation and distribution.
The model has expanded from the sharing of rooms and cars - via companies such as Airbnb, Uber and Zipcar - to dresses, outdoor gear, parking spots and even bulldozers.
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