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The lab has long had a National Cancer Institute designated Cancer Center where work using genomics, RNAi screens, and mouse models has yielded important cancer drug targets.
Analysis of these models has yielded answers to the question of why it is so difficult to eradicate biofilms using biocides.
Although the epidemiologic association of the genes encoding PVL with CA-MRSA strains is compelling [20], investigation of the role of PVL in rodent models has yielded conflicting results, possibly because of interspecies variability in susceptibility of neutrophils to the toxic effects of PVL [46].
Imaging in animal models has yielded similar results (Min et al., 2012; Lai et al., 2013).
Competition between colicin producing and sensitive strains in mouse models has yielded outcomes ranging from eradication of the sensitive strain to long-term coexistence [ 9, 51– 54], our results suggest that variations in nutrient conditions may explain these differences.
While much of the in vivo evidence linking Aβ and α-syn comes from the use of transgenic mice that express mutant genes, the study of these models has yielded invaluable additions to our knowledge of neurodegenerative disease [ 1, 18, 37].
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The models have yielded different results.
We review how mathematical models have yielded useful insights into controlling disease spread for other vector-borne plant diseases, and the small number of mathematical models of HLB.
Sophisticated thermal hydrological (TH) conceptual models have yielded a good fit between simulation results and those measured data.
While patients and other models have yielded important clinical insights into this disease, we were particularly interested in its molecular aspects—how specific genes can affect responses to glucose by the beta cell," said co-senior author Dieter Egli, PhD, Senior Research Fellow at NYSCF, who was named a NYSCF Robertson Stem Cell Investigator in 2012.
Based on high-speed schlieren imaging of the interaction between the 3D printed scramjet inlet and the hypersonic airflow, these 3D printed models have yielded satisfactory aerodynamic performance, showing reasonable thermal and structural survivability under dynamic pressure around 58,6 MPa.
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