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Cell sheet transplantation onto damaged hearts in several animal models has revealed improvements in heart functions.
Genetic analysis of Lats/Wts family genes using Drosophila and mice models has revealed their role as negative growth regulators and tumor suppressors in animal (Visser and Yang, 2010; Harvey et al., 2013; Yu and Guan, 2013).
Work with BC1 and Fmr1 animal models has revealed that phenotypical consequences resulting from the absence of either BC1 RNA or FMRP are remarkably similar.
Our work with P. infestans, which has a different evolutionary history than the prior-studied models, has revealed new roles of Cdc14, and raised questions about its ancestral function and how eukaryotes evolved.
Studying cancer susceptibility in mouse models has revealed opposite allele effects across different genetic backgrounds [ 68].
Studying tissue samples from AKU patients and from AKU mouse models has revealed significant parallels with the pathophysiology of OA.
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Acute In vitro models have revealed a great deal of information about mechanisms underlying many types of epileptiform activity.
Several animal models have revealed that platelet-derived serotonin initiates liver regeneration after hepatectomy.
Our new tissue culture models have revealed virus-like particle arrays (at left) that correspond to isolated infectious brain particles of ~25nm.
Several studies using animal models have revealed an inverse relation between gluco-corticoid levels and hippocampus volumes.
In vivo studies in murine models have revealed that IL-8 produced by melanoma cells is involved in neutrophil activation and chemotaxis, which results in increased metastatic homing to the lung156.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com