Sentence examples for models has hampered from inspiring English sources

As for many human specific diseases, the difficulty of reproducing the human disease in animal models has hampered the identification of the neisserial attributes required for invasiveness.

However, for many human diseases, and in particular in the case of meningococcal meningitis, the difficulty of reproducing the human disease in animal models has hampered the identification of novel virulence factors.

This mutation reduces frataxin expression, but the lack of good models has hampered attempts to understand the pathogenesis of FRDA.

Current treatments are only palliative in nature, and the lack of suitable pre-clinical models has hampered previous efforts to develop novel therapeutic strategies.

The lack of a suitable cellular paradigm and/or animal models has hampered studies on mitochondrial biogenesis at the early stages of neurogenesis.

Lack of in vivo models have hampered efforts to identify potential therapeutic targets.

The lack of an effective cell culture system and a small animal model has hampered the progress of HEV research.

However, lack of a robust and convenient small animal model has hampered the assessment of in vivo efficacy of any antiviral compound.

An oncogenic role for JCV has been demonstrated in several animal studies including rodents and primates (reviewed in [30]), but the lack of an adequate in vitro model has hampered our understanding of the role of JCV in human cancer.

The limited representative EBV infection model has hampered research on the relationship between EBV and NPC.

However, there is a general lack of suitable animal models that has hampered the studies of myocardial hibernation.