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The development of genetically engineered mouse models has enabled detailed study of the regulation of fetal mineral homeostasis.
The development of genetically engineered mouse models has enabled detailed study of the regulation of maternal mineral homeostasis during pregnancy and lactation.
The integration of available genomic and metabolomic data through the generation of genome scale metabolic models has enabled the development of computational models that predict the behaviour of organisms under specific conditions and present a route to metabolic engineering.
While the host parasite relationship in humans has been difficult to determine, the pliability of murine malaria models has enabled valuable contributions to the understanding of the pathogenesis of disease.
A variety of genetically-engineered mouse models has enabled the identification of various genes involved in mammary cancer initiation and progression, yet the resulting tumors often differ in their pathology compared to human breast cancers [ 33].
27 Thus, utilization of Wld S mice and other mouse models has enabled us to identify and evaluate asynchronous synaptic degeneration in both investigator-triggered and spontaneous synaptic degeneration.
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Advances in computer-based models have enabled companies to tie production schedules more closely to customer delivery schedules while increasing the rate of plant utilization.
In vitro biomaterial models have enabled advances in understanding the role of extracellular matrix (ECM) architecture in the control of cell motility and polarity.
Advancements in imaging technologies, genetic recombination techniques, laser ablation, and microfabricated tissue models have enabled quantitative descriptions of the cellular motions and tissue deformations and stresses with unprecedented temporal and spatial resolution.
These computation models have enabled designers to work with complex geometry and numeric design constraints to explore a whole new design field that is impossible to explore without computation techniques.
In this regard, these models have enabled description of a complex sequence of events involving T cells, B cells, dendritic cells, mast cells, macrophages, eosinophils, epithelial cells, and endothelial cells.
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