Sentence examples for models harbor all from inspiring English sources

a The primary models harbor all variables.

In agreement with other models harboring a specific ATP synthase deficiency (37– 39), mitochondria from Lrpprc knockout hearts can maintain ΔΨ in the non-phosphorylating state, but are hyperpolarized under phosphorylating conditions (Fig.  5B and C, Supplementary Material, Fig. S3A).

Given the established clinical importance of cyclin D1b induction, novel models harboring a genetic switch from cyclin D1a to cyclin D1b were generated herein and uncovered the effects of the switch to cyclin D1b expression on developmental and cellular transformation phenotypes.

All models harbor advantages and disadvantages.

The secondary models harbor influential (VIP > 1.0) markers from the corresponding primary models M1 to M4.

This might lead to significant bias in the assessment of N-truncated Aβ variants in transgenic mouse models and the fact that most available models harbor the Swedish APP mutation favoring the generation of full-length Aβ peptides may skew results even further.

In this study, we have demonstrated that a prolonged metabolic failure due to mitochondrial dysfunction, either in cellular models harboring sPD subjects mtDNA (sPD cybrids) or knock-down of all mtDNA (Rho0 cells) or in MPP+-treated cortical neurons, causes a functional decline in the activity of the autophagic system.

However, these approaches have only been demonstrated in human tumor-derived cell lines or mouse models harboring mtDNA mutations.

Animal models harboring defects in the ATP7B homolog have helped to reveal new insights into pathomechanisms of WD.

Development of animal models harboring mtDNA mutations is crucial to elucidating pathways of disease and as models for preclinical assessment of therapeutic interventions.

Here, we describe methodology to produce transmitochondrial mice (both homoplasmic and heteroplasmic models) harboring foreign mitochondrial genomes, using both embryo microinjection and embryonic stem (ES) cell-based approaches.