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A crucial role of MMPs in mediating neuronal death in the developing mammalian brain has been demonstrated in animal models for traumatic, ischemic, and epileptic brain damage [11],[11].
One of the most used prognostic models for traumatic brain injury is the IMPACT-TBI model, which predicts 6-month mortality and unfavorable outcome.
In recent studies, anisotropy of brain tissue was incorporated in full-scale numerical head models for traumatic brain injury to demonstrate the importance of orientation-dependent mechanical properties of the tissue (Giordano et al. 2014; Wright et al. 2013).
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A biomechanical model for traumatic brain injury and soft tissue damage is presented.
Relying too heavily on epilepsy as a model for traumatic brain injury could also be problematic, says neuropsychologist James Sumowski of the Kessler Foundation in West Orange, New Jersey.
To investigate further the cell death in our in-vitro model for traumatic joint injury, we performed a quantitative analysis by electron microscopy (EM) of cell morphology after injurious compression.
We used a mouse model for traumatic gastrocnemius muscle injury.
The middle cerebral artery occlusion model is considered a reasonable model for traumatic hemorrhagic contusion (John Povlishock, personal communication).
This study is aimed at developing a high quality, validated finite element (FE) human head model for traumatic brain injuries (TBI) prediction and prevention during vehicle collisions.
These properties are particularly important for modeling Traumatic Brain Injury (TBI).
Mechanical characterization of brain tissue at high loading velocities is crucial for modeling Traumatic Brain Injury (TBI).
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