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Chalmers et al. state that about 85%% of the global annual investment in biomedical research is currently wasted, [ 6] even though effective strategies and models for stepwise implementation of new evidence exist.
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The model for stepwise regression contained, with lean mass, 1 of the 4 predictors and was achieved in 1 step.
Addition and omission of one regression term had to significantly change the r square (=explained variance) of the regression model for stepwise inclusion as being tested by the F-test [ 28, 29].
At the second step of modeling, reported in Table 1 under the 'Stepwise multivariate logistic regression' heading all baseline variables that were identified as potentially significant (p < 0.1 in the single factor model) were simultaneously included in a multivariate model for stepwise selection of covariates based on significance cut-off of p < 0.1 entry into the combined model.
The OR estimates from the final models for the stepwise approaches were at least 1.5.
We established models for the stepwise gastrointestinal investigation by placing three-way pipes at the gastroduodenal junction and at the terminal ileum and collecting discharges from the anus.
A simple but realistic model, both for stepwise periodic and controlled cycling operation and a simulation algorithm are proposed.
A mixed-integer linear programming model dedicated for stepwise capacity expansion strategies for chemical process plants forms the core of the tool.
If less restrictive selection criteria were used for including a variable in the model (probability for stepwise entry 0.1 and removal 0.2), the factors needle path through ventilated lung and acute angle of the needle to the surface of the tumor also occur in the models (Table 4) This study is the first one to identify risk factors for the occurrence of an SAE that depend on the biopsy technique.
The models for predicting stepwise-FP with respect to different dosing times and/or asymmetrical doses were developed, and were found to be very useful for evaluating the system performance and/or for process design.
Stepwise mutation models, which allow for stepwise changes of repeat size of alleles, have been extensively used to study MSs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com