Final models were adjusted for district and year of birth, and in further models, for season and number of prior live births.
We adjusted models for season of onset because, as expected, MRSA patients with onset in the winter had low exposure to treated crop fields (manure application is restricted in the winter).
The diurnal variations of GPS-TEC and different IRI models, for three seasons winter (November, December, January, and February), summer (May, June, July, and August), and equinox (March, April, September, and October) are shown in Figure 3.
We however built separate models for different seasons and found that the relationship exists between OCC and cholera only during the pre-monsoon period.
No other associations were evident in models adjusted for season in addition to those model covariates selected a priori.
Using mechanistic models for in-season yield forecasts may help to optimize crop management decisions such as absolute fertilizer rates.
Data were analyzed using random effects models adjusting for season, weekday, and meteorology.
Moreover, the strong correlation between season and exposure, particularly for the trimester-specific exposure variables, was likely to make the estimates of our regression models adjusted for season instable.
In the models adjusted for season, an increase of the NK-cell fraction was also seen (+2.5%; 95% CI, 0.2 to 4.7%); additional adjustment for 3-day temperature reduced the magnitude of associations, but most remained significant (Table 3).
In models adjusting for season, the within-home variance was less than the between-home variance for all three rooms, suggesting that factors affecting endotoxin levels within a home over time influence the total variability less than factors contributing to home-to-home differences in endotoxin.
