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The proposed simulation algorithm can also be applied to simulate the recurrence process in joint models for recurrent events and a terminal event [ 28, 29].
Procedures for estimating the parameters of the general class of semiparametric models for recurrent events proposed by Peña and Hollander [(2004). Models for recurrent events in reliability and survival analysis. In: Soyer R., Mazzuchi T., Singpurwalla N. (Eds)., Mathematical Reliability: An Expository Perspective. Kluwer Academic Publishers, Dordrecht, pp. 105 123 (Chapter 6)] are developed.
Pena et al [ 19] and Pena et al [ 20] also discussed the general class of semi-parametric models for recurrent events.
Cox models for recurrent falls showed that intervention had a negative effect (hazard ratio [HR] 1.46, 95% CI 1.03 2.09) and that functional impairment (HR 1.42, 95% CI 0.97 2.12), previous falls (HR 1.09, 95% CI 0.74 1.60), and cognitive impairment (HR 1.08, 95% CI 0.72 1.60) had no effect on the assessment.
Statistical models for recurrent events are of great interest in repairable systems reliability and maintenance.
Association between outcome and potential risk factors was assessed in univariate and multivariate extended Poisson models for recurrent events (gamma frailty model) [ 12].
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ABSOLUTE [ 122] uses data from copy number variations for optimizing models of recurrent cancer karyotypes and expected allelic fraction values for somatic SNVs.
The Andersen-Gill model (A-G model), an extension of the standard Cox proportional hazard model for recurrent events, accommodates censored data and time-dependent covariates (Fleming and Harrington 1991; Therneau and Grambsch 2000).
To account for the recurrent events and their association with the risk of death, we used a joint frailty model for recurrent events and a terminal event.
Here, our main goal is to validate a method of predictions from a joint model for recurrent events and death as accurate predictions.
To determine risk factors for recurrent events, we used an extension of the Cox proportional hazards model for recurrent event data, the Prentice, Williams and Peterson gap time (PWP-GT) model [ 18].
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